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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG2
All Species:
19.7
Human Site:
S218
Identified Species:
33.33
UniProt:
Q9UNQ0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNQ0
NP_004818.2
655
72314
S218
E
P
T
T
G
L
D
S
S
T
A
N
A
V
L
Chimpanzee
Pan troglodytes
XP_526633
860
94544
S423
E
P
T
T
G
L
D
S
S
T
A
N
A
V
L
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
S218
E
P
T
T
G
L
D
S
S
T
A
N
A
V
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMS5
657
72959
S217
E
P
T
T
G
L
D
S
S
T
A
N
A
V
L
Rat
Rattus norvegicus
Q80W57
657
72942
S217
E
P
T
T
G
L
D
S
S
T
A
N
A
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510302
654
72378
A215
E
P
T
T
G
L
D
A
S
T
A
N
A
V
L
Chicken
Gallus gallus
XP_421638
651
72109
A220
E
P
T
T
G
L
D
A
S
T
A
N
A
V
L
Frog
Xenopus laevis
NP_001091141
661
73548
A216
E
P
T
T
G
L
D
A
S
T
A
N
A
V
L
Zebra Danio
Brachydanio rerio
NP_001036240
643
71395
L211
L
D
E
P
T
T
G
L
D
A
S
T
A
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
E254
K
R
L
A
F
A
S
E
A
L
T
D
P
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
V175
D
A
F
M
A
G
H
V
V
Q
A
L
R
S
L
Sea Urchin
Strong. purpuratus
XP_789781
628
69714
G205
L
A
I
L
S
K
Q
G
R
A
I
I
F
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YS4
751
82913
V241
L
K
S
K
I
G
F
V
T
Q
D
D
V
L
F
Baker's Yeast
Sacchar. cerevisiae
P25371
1049
117213
S563
P
T
S
G
L
D
A
S
N
A
N
N
V
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
96.6
N.A.
N.A.
81.8
81.4
N.A.
75.8
62.4
68.2
60.9
N.A.
31.5
N.A.
29.6
45
Protein Similarity:
100
75.9
97.7
N.A.
N.A.
89.6
89.1
N.A.
88.2
78.3
82.1
77.8
N.A.
51.6
N.A.
48.4
63.8
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
93.3
93.3
6.6
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
100
100
100
13.3
N.A.
26.6
N.A.
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
8
8
8
8
22
8
22
65
0
65
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
8
58
0
8
0
8
15
0
0
0
% D
% Glu:
58
0
8
0
0
0
0
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
0
8
0
8
% F
% Gly:
0
0
0
8
58
15
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
0
0
0
0
8
8
0
8
8
% I
% Lys:
8
8
0
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
22
0
8
8
8
58
0
8
0
8
0
8
0
8
72
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
65
0
8
0
% N
% Pro:
8
58
0
8
0
0
0
0
0
0
0
0
8
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
15
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% R
% Ser:
0
0
15
0
8
0
8
43
58
0
8
0
0
15
8
% S
% Thr:
0
8
58
58
8
8
0
0
8
58
8
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
15
8
0
0
0
15
58
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _